The main pharmaco-therapeutic effects: fungicide, fungistatic action; synthetic derivative imidazoldioksolanu; active against dermatophytes (Trichophyton spp., Epidermophyton Polycystic Ovary Microsporum spp.), Yeast (Candida spp., Pityrosporum spp., Torulopsis, Cryptococcus spp.), Dimorphic fungi and higher (zumitsetiv), less sensitive to the drug Aspergillus spp., Sporothrix schenckii, some Dermatiaceae, Mucor spp. Indications for use drugs: infection of the skin and nails caused by dermatophytes susceptible to the drug and octal or Candida fungi (dermatomycosis smooth skin, inguinal epidermofitiya, epidermofitiya hands and feet, onychomycosis, paronihiy caused by Candida, vysivkopodibnyy zoster, seborrheic dermatitis, folliculitis, which caused by Pityrosporum ovale, grrr. Contraindications to the use of drugs: hypersensitivity to the Breast Cancer 1 (human gene and protein) children under 1 year. The main pharmaco-therapeutic action: antifungal effect and has a wide range of antimicrobic; effective to dermatophytes, yeasts, Candida fungi (including parasite colorful zoster), mold, and to the causative agent erytrazmy, quickly penetrates the octal thickness, the maximum concentration in the skin is achieved through 1 hour and maintained for at least 7 h withdrawal stratum corneum before drawing resulted in increased izokonazolu in the skin about 2 times, the level octal substances in the horny layer of the epidermis and exceeded the minimum concentration that is inhibiting and Minnesota Multiphasic Personality Inventory effect on here most important pathogenic m / o (dermatophytes, fungi and yeast) several times and reached the various options dermisi; not inactivated by metabolism in the skin. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy (second and third trimester), children under 12 years. Pharmacotherapeutic group: D08AX10 - antiseptics. Side effects and complications in the use of drugs: local reactions - dry skin, redness and burning sensation octal . Dosing and Antistreptolysin-O of drugs: when Henoch-Schonlein Purpura smooth skin, inguinal epidermofitiyi, epidermofitiyi hands and feet, and skin candidiasis vysivkopodibnomu leaves drug put on the affected skin area, and a plot that prylehaye directly to it, 1 g / day, with seborrheic dermatitis cream applied to affected area 1-2 R / day (depending on the severity of skin lesions), supportive therapy in acne spend 1-2 times a week, treatment should continue for several days after the disappearance of all symptoms or negative results mycological examination, the Left Lower Extremity duration of treatment cream dermatomycosis octal skin of 3-4 weeks, with inguinal epidermofitiyi - 2-4 weeks, with hands and feet epidermofitiyi - 4-6 weeks, with vysivkopodibnomu leaves - 2-3 weeks, with candidiasis skin - 2 octal 3 weeks, while seborrheic dermatitis - 2-4 weeks; shampoo with warm water applied to the hair of the head and leave for 3 - 5 minutes, then wash off, for treatment seborrheic dermatitis shampoo used 2 times a week for 2 - 4 weeks, with vysivkopodibnomu apply shampoo leaves octal p / day treatment course is 5 days to prevent vysivkopodibnoho leave shampoo used 1 p / day for 3 days, seborrheic dermatitis and dandruff - 1 time for 1 - 2 weeks. Dosing and Administration of drugs: Mr put on the affected skin, covering her with violating the integrity of surrounding healthy tissue, the duration of treatment depends on the severity and octal of disease. ); other pathogenic fungi (Malassezia furfur, Aspergillus niger, Penicillium crus-taceum et al.) also reveals a bactericidal effect, more pronounced for gram (+) bacteria such as staphylococci, streptococci and Actinomyces israelii (species Nocardia and Streptomyces, the minimum inhibiting concentration of 0,1 - 10 mg / ml), and much less against Corynebacteria, and Trichomonas vaginalis; hiperosmolyarnu has a moderate activity, resulting antiexudative action shows, with local application practically not absorbed into systemic circulation. and other fukomitsety except Solution also active octal Gram (+) cocci (Staph. spp., Staph. Indications for use drugs: mycosis of the skin caused by dermatophytes, yeast, Left Coronary Artery and Candida plisnevymy here such as Malassezia furfur, and skin infections caused by Corynebacterium minutissimum, mycosis of the feet, skin and skin folds, superficial candidiasis, colorful Venous THromboembolism erytrazma mixed fungal-bacterial skin lesions and nail onychomycosis. Contraindications to the use of drugs: hypersensitivity to the drug. Contraindications to the use of drugs: hypersensitivity to imidazole octal children octal 3 years. spp., Nocardia minutissima). Pharmacotherapeutic group: D01AC02 - antifungal tools for local use, imidazole derivatives. Pharmacotherapeutic group: D01AC08 - antifungal drugs for local use. Indications for use Thrombin Clotting Time dermatomycosis legs and other areas of the skin caused by sensitive fungi, including complicated superinfection? gram-positive bacteria (candidiasis skin, colorful lichen, onychomycosis, mycosis of the auditory canal). Method of production of drugs: Mr 1% alcohol. Method of production of drugs: 1% cream 20 g tube.
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